Aerobic Bioprocess: Modelling and Control


Prof. Mihai Caramihai
Professor of Computer Science
POLITEHNICA University of Bucharest

Abstract: In this overview, the most important and recent issues regarding the modeling and the control of the aerobic bioprocess are discussed: (a) modeling and control role; (b) instruments and techniques for bioprocess variables determination and monitoring; (c) the mathematical modeling (unstructured global models; structured models; segregated models; metabolic modeling); (d) bioprocess control techniques (model based, adaptive or artificial intelligence control); (e) case study: control of the fed-batch bioprocess of alcoholoxidase formation with the yeast Hansenula polymorpha.


Plenary Speakers' Brief Biography: Mihai Caramihai is Professor of Computer Science at POLITEHNICA University of Bucharest (where he has been since 1989) and Expert with the European Commission / National Agency for Community Programmes in the Field of Education and Vocational Training (Romania). Professor Caramihai is the author of more than 17 scientific books and 180 technical papers and is involved both in research and project management activities and he holds one patent deriving from his research. He is a member of 4 Royal Societies and more than 20 Professional Societies.

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